9K9L
Cryo-EM structure of the human CENP-A-H4 octasome.
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | DNA_BIND: |
| Chain | Residue | Details |
| B | LYS16-LYS20 | |
| D | LYS16-LYS20 | |
| F | LYS16-LYS20 | |
| H | LYS16-LYS20 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:17967882 |
| Chain | Residue | Details |
| B | SER1 | |
| D | SER1 | |
| F | SER1 | |
| H | SER1 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5 and PRMT7; alternate => ECO:0000250|UniProtKB:P62806 |
| Chain | Residue | Details |
| B | ARG3 | |
| D | ARG3 | |
| F | ARG3 | |
| H | ARG3 | |
| E | SER17 | |
| E | SER19 | |
| G | SER17 | |
| G | SER19 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-lactoyllysine; alternate => ECO:0000269|PubMed:31645732 |
| Chain | Residue | Details |
| B | LYS5 | |
| D | LYS5 | |
| F | LYS5 | |
| H | LYS5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | MOD_RES: N6-propionyllysine; alternate => ECO:0000269|PubMed:17267393 |
| Chain | Residue | Details |
| B | LYS8 | |
| H | LYS8 | |
| H | LYS16 | |
| H | LYS44 | |
| B | LYS16 | |
| B | LYS44 | |
| D | LYS8 | |
| D | LYS16 | |
| D | LYS44 | |
| F | LYS8 | |
| F | LYS16 | |
| F | LYS44 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435 |
| Chain | Residue | Details |
| B | LYS12 | |
| F | LYS31 | |
| F | LYS77 | |
| F | LYS91 | |
| H | LYS12 | |
| H | LYS31 | |
| H | LYS77 | |
| H | LYS91 | |
| B | LYS31 | |
| B | LYS77 | |
| B | LYS91 | |
| D | LYS12 | |
| D | LYS31 | |
| D | LYS77 | |
| D | LYS91 | |
| F | LYS12 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:12086618, ECO:0000269|PubMed:15964846, ECO:0000269|PubMed:17967882, ECO:0000269|PubMed:27338793 |
| Chain | Residue | Details |
| B | LYS20 | |
| D | LYS20 | |
| F | LYS20 | |
| H | LYS20 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by PAK2 => ECO:0000269|PubMed:21724829, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| B | SER47 | |
| D | SER47 | |
| F | SER47 | |
| H | SER47 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15592455, ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| B | TYR51 | |
| D | TYR51 | |
| F | TYR51 | |
| H | TYR51 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-glutaryllysine; alternate => ECO:0000269|PubMed:31542297 |
| Chain | Residue | Details |
| B | LYS59 | |
| D | LYS59 | |
| F | LYS59 | |
| H | LYS59 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62806 |
| Chain | Residue | Details |
| B | LYS79 | |
| D | LYS79 | |
| F | LYS79 | |
| H | LYS79 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P62806 |
| Chain | Residue | Details |
| B | THR80 | |
| D | THR80 | |
| F | THR80 | |
| H | THR80 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| B | TYR88 | |
| D | TYR88 | |
| F | TYR88 | |
| H | TYR88 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447 |
| Chain | Residue | Details |
| B | LYS12 | |
| D | LYS12 | |
| F | LYS12 | |
| H | LYS12 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:19818714 |
| Chain | Residue | Details |
| B | LYS91 | |
| D | LYS91 | |
| F | LYS91 | |
| H | LYS91 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 12 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| B | LYS20 | |
| H | LYS20 | |
| H | LYS59 | |
| H | LYS79 | |
| B | LYS59 | |
| B | LYS79 | |
| D | LYS20 | |
| D | LYS59 | |
| D | LYS79 | |
| F | LYS20 | |
| F | LYS59 | |
| F | LYS79 |
| site_id | SWS_FT_FI17 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate => ECO:0000269|PubMed:30886146 |
| Chain | Residue | Details |
| B | LYS31 | |
| D | LYS31 | |
| F | LYS31 | |
| H | LYS31 |
