9K1R
Structure of SF3B core in complex with the intron-U2 snRNA (SF3B-intron-U2 snRNA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Splicing factor 3B subunit 1 | polymer | 897 | 101192.7 | 1 | UniProt (O75533) Pfam (PF22646) | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 155 kDa subunit,SF3b155,Spliceosome-associated protein 155,SAP 155 |
| 2 | B (D) | PHD finger-like domain-containing protein 5A | polymer | 110 | 12427.5 | 1 | UniProt (Q7RTV0) Pfam (PF03660) | Homo sapiens (human) | PHD finger-like domain protein 5A,Splicing factor 3B-associated 14 kDa protein,SF3b14b |
| 3 | C (A) | Splicing factor 3B subunit 3 | polymer | 1224 | 136678.9 | 1 | UniProt (Q15393) Pfam (PF10433) Pfam (PF03178) | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 130 kDa subunit,SF3b130,STAF130,Spliceosome-associated protein 130,SAP 130 |
| 4 | D (B) | Splicing factor 3B subunit 5 | polymer | 86 | 10149.4 | 1 | UniProt (Q9BWJ5) Pfam (PF07189) | Homo sapiens (human) | SF3b5,Pre-mRNA-splicing factor SF3b 10 kDa subunit |
| 5 | E (G) | pre-mRNA intron | polymer | 34 | 10718.4 | 1 | Homo sapiens | ||
| 6 | F (H) | U2 snRNA | polymer | 18 | 5705.3 | 1 | Homo sapiens | ||
| 7 | G, H, I (D) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
C: 453 - 1304 (UniProt: O75533)
A: 1 - 1217 (UniProt: Q15393)
| PDB | External Database | Details |
|---|---|---|
| Met 408 | - | initiating methionine |
| Ala 409 | - | expression tag |
| Ser 410 | - | expression tag |
| Ala 411 | - | expression tag |
| Trp 412 | - | expression tag |
| Ser 413 | - | expression tag |
| His 414 | - | expression tag |
| Pro 415 | - | expression tag |
| Gln 416 | - | expression tag |
| Phe 417 | - | expression tag |
| Glu 418 | - | expression tag |
| Lys 419 | - | expression tag |
| Gly 420 | - | expression tag |
| Gly 421 | - | expression tag |
| Gly 422 | - | expression tag |
| Ser 423 | - | expression tag |
| Gly 424 | - | expression tag |
| Gly 425 | - | expression tag |
| Gly 426 | - | expression tag |
| Ser 427 | - | expression tag |
| Gly 428 | - | expression tag |
| Gly 429 | - | expression tag |
| Ser 430 | - | expression tag |
| Ala 431 | - | expression tag |
| Trp 432 | - | expression tag |
| Ser 433 | - | expression tag |
| His 434 | - | expression tag |
| Pro 435 | - | expression tag |
| Gln 436 | - | expression tag |
| Phe 437 | - | expression tag |
| Glu 438 | - | expression tag |
| Lys 439 | - | expression tag |
| Ser 440 | - | expression tag |
| Asp 441 | - | expression tag |
| Leu 442 | - | expression tag |
| Glu 443 | - | expression tag |
| Val 444 | - | expression tag |
| Leu 445 | - | expression tag |
| Phe 446 | - | expression tag |
| Gln 447 | - | expression tag |
| Gly 448 | - | expression tag |
| Pro 449 | - | expression tag |
| Leu 450 | - | expression tag |
| Gly 451 | - | expression tag |
| Ser 452 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 276872.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 277068.4 |
