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9K0J

Crystal structure of FGFR4 kinase domain with 43b

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Fibroblast growth factor receptor 4polymer31134663.01UniProt (P22455)
Pfam (PF07714)
Homo sapiens (human)FGFR-4
2B
(A)
~{N}-[5-[(1~{R})-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1~{H}-indazol-3-yl]-2-fluoranyl-6-(propanoylamino)benzamidenon-polymer516.41Chemie (A1EEX)
3C, D, E, F, G
(A)
SULFATE IONnon-polymer96.15Chemie (SO4)
4H, I
(A)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.12Chemie (TRS)
5J
(A)
waterwater18.0224Chemie (HOH)
Sequence modifications
A: 445 - 753 (UniProt: P22455)
PDBExternal DatabaseDetails
Gly 443-expression tag
Pro 444-expression tag
Ala 477Cys 477conflict
Glu 664Arg 664conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34663.0
Non-Polymers*Number of molecules8
Total formula weight1241.0
All*Total formula weight35903.9
*Water molecules are not included.

248942

PDB entries from 2026-02-11

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