9JNN

Structure of native di-heteromeric GluN1-GluN2B NMDA receptor in rat cortex and hippocampus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Glutamate receptor ionotropic, NMDA 1	polymer	817	91996.2	2	UniProt (P35439) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1
2	B, D (B, D)	Glutamate receptor ionotropic, NMDA 2B	polymer	811	91182.1	2	UniProt (Q00960) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	GluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NMDAR2B,NR2B
3	E, I (E, I)	Heavy Chain of GluN1 Fab, 4F11	polymer	118	13306.7	2		Mus musculus
4	F, J (F, J)	Light Chain of GluN1 Fab, 4F11	polymer	110	11784.0	2		Mus musculus
5	G, K (G, K)	Heavy Chain of GluN2B Fab2	polymer	118	12994.5	2		Mus musculus
6	H, L (H, L)	Light Chain of GluN2B Fab2	polymer	106	11659.0	2		Mus musculus
7	M, N, P, Q (M, N, P, Q)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
8	O, R (O, R)	alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G62182OO)
9	AA, BA, CA, DA, EA... (C, D, A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	14	Chemie (NAG)
10	HA, Z (D, B)	(2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid	non-polymer		252.2	2	Chemie (7RC)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	465845.0
Branched	Number of molecules	6
	Total formula weight	2870.7
Non-Polymers*	Number of molecules	16
	Total formula weight	3601.3
All*	Total formula weight	472317.0

*Water molecules are not included.