9JIZ
Macrophage migration inhibitory factor S61H/Y100H mutant complexed with three Zinc ions (Zn3-MIF(S61H/Y100H))
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Macrophage migration inhibitory factor | polymer | 115 | 12512.3 | 3 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (human) | MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase |
| 2 | D, J, N (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E (A) | CARBONATE ION | non-polymer | 60.0 | 1 | Chemie (CO3) | |||
| 4 | F, G, K, O (A, B, C) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | H, L, P (A, B, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | I, M, Q, R (A, B, C) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 4 | Chemie (IPA) | |||
| 7 | S, T, U (A, B, C) | water | water | 18.0 | 510 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 115 (UniProt: P14174)
| PDB | External Database | Details |
|---|---|---|
| His 61 | Ser 61 | engineered mutation |
| His 100 | Tyr 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37536.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1157.2 | |
| All* | Total formula weight | 38694.0 |
