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9JH2

Crystal Structure of NFIA in Complex with DNA containing the TGGCA Motif

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Nuclear factor 1 A-typepolymer16519272.71UniProt (Q12857)
Pfam (PF10524)
Pfam (PF03165)
Homo sapiens (human)NF1-A,Nuclear factor 1/A,CCAAT-box-binding transcription factor,CTF,Nuclear factor I/A,NF-I/A,NFI-A,TGGCA-binding protein
2B
(B)
DNA (5'-D(*AP*GP*TP*TP*GP*GP*CP*AP*AP*GP*TP*C)-3')polymer123702.41synthetic construct
3C
(C)
DNA (5'-D(*GP*AP*CP*TP*TP*GP*CP*CP*AP*AP*CP*T)-3')polymer123622.41synthetic construct
4D
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5E, F, G
(A, B, C)
waterwater18.045Chemie (HOH)
Sequence modifications
A: 13 - 175 (UniProt: Q12857)
PDBExternal DatabaseDetails
Gly 11-expression tag
Ser 12-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight26597.5
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight26662.9
*Water molecules are not included.

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PDB entries from 2026-03-18

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