9J7I

Cryo-EM Structure of calcium sensing receptor in complex gamma-glutamyl-valyl-glycine as a kokumi substance

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Extracellular calcium-sensing receptor	polymer	902	101745.4	1	UniProt (P41180) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003)	Homo sapiens (human)	CaR,CaSR,hCasR,Parathyroid cell calcium-sensing receptor 1,PCaR1
2	B (B)	gamma-glutamyl-valyl-glycine	polymer	3	303.3	1		synthetic construct

Sequence modifications

A: 19 - 894 (UniProt: P41180)

PDB	External Database	Details
Met -7	-	initiating methionine
Lys -6	-	expression tag
Thr -5	-	expression tag
Ile -4	-	expression tag
Ile -3	-	expression tag
Ala -2	-	expression tag
Leu -1	-	expression tag
Ser 0	-	expression tag
Tyr 1	-	expression tag
Ile 2	-	expression tag
Phe 3	-	expression tag
Cys 4	-	expression tag
Leu 5	-	expression tag
Val 6	-	expression tag
Phe 7	-	expression tag
Ala 8	-	expression tag
Asp 9	-	expression tag
Tyr 10	-	expression tag
Lys 11	-	expression tag
Asp 12	-	expression tag
Asp 13	-	expression tag
Asp 14	-	expression tag
Asp 15	-	expression tag
Lys 16	-	expression tag
Ala 17	-	expression tag
Ala 18	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	102048.8
All*	Total formula weight	102048.8

*Water molecules are not included.