9J6L
Solution structure of human Glutathione Peroxidase 4 (Sec73Cys) with eight mutations
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phospholipid hydroperoxide glutathione peroxidase GPX4 | polymer | 174 | 19851.6 | 1 | UniProt (P36969) Pfam (PF00255) | Homo sapiens (human) | PHGPx,Glutathione peroxidase 4,GPx-4,GSHPx-4 |
Sequence modifications
A: 26 - 197 (UniProt: P36969)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Pro 25 | - | expression tag |
| His 27 | Thr 27 | engineered mutation |
| Ser 29 | Cys 29 | engineered mutation |
| Ala 37 | Cys 37 | engineered mutation |
| Ser 64 | Cys 64 | engineered mutation |
| Cys 73 | Sec 73 | engineered mutation |
| Arg 93 | Cys 93 | engineered mutation |
| Ser 102 | Cys 102 | engineered mutation |
| Glu 134 | Cys 134 | engineered mutation |
| Val 175 | Cys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19851.6 | |
| All* | Total formula weight | 19851.6 |
