9J54

Crystal structure of FIP200 Claw in complex with ATG16L1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	RB1-inducible coiled-coil protein 1	polymer	111	12614.6	2	UniProt (Q8TDY2) Pfam (PF10377)	Homo sapiens (human)	FAK family kinase-interacting protein of 200 kDa,FIP200
2	B, D (B, D)	Autophagy-related protein 16-1	polymer	17	1817.8	2	UniProt (Q676U5) UniProt (by SIFTS) (E7EVC7)	Homo sapiens (human)	APG16-like 1
3	E, F, G, H (A, B, C, D)	water	water		18.0	139	Chemie (HOH)

Sequence modifications

A, C: 1490 - 1594 (UniProt: Q8TDY2)

PDB	External Database	Details
Gly -6	-	expression tag
Pro -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Glu -2	-	expression tag
Phe -1	-	expression tag

B, D: 235 - 247 (UniProt: Q676U5)

PDB	External Database	Details
Gly 231	-	expression tag
Pro 232	-	expression tag
Gly 233	-	expression tag
Ser 234	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	28864.7
All*	Total formula weight	28864.7

*Water molecules are not included.