9IQY
Cryo-EM structure of human TRPV4 intracellular domain in complex with GTPase RhoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, C) | Transient receptor potential cation channel subfamily V member 4 | polymer | 640 | 73038.7 | 2 | UniProt (Q9HBA0) Pfam (PF00023) Pfam (PF00520) | Homo sapiens (human) | TrpV4,Osm-9-like TRP channel 4,OTRPC4,Transient receptor potential protein 12,TRP12,Vanilloid receptor-like channel 2,Vanilloid receptor-like protein 2,VRL-2,Vanilloid receptor-related osmotically-activated channel,VR-OAC |
| 2 | C (J) | Transforming protein RhoA | polymer | 193 | 21799.2 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (human) | Rho cDNA clone 12,h12 |
| 3 | D (J) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | E (J) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 167876.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 467.5 | |
| All* | Total formula weight | 168344.1 |
