9IQT

structure of niacin-HCA2-Gi

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	R	Hydroxycarboxylic acid receptor 2	polymer	363	41897.4	1	UniProt (Q8TDS4) In PDB	Homo sapiens (human)	G-protein coupled receptor 109A,G-protein coupled receptor HM74A,Niacin receptor 1,Nicotinic acid receptor
2	A	Guanine nucleotide-binding protein G(i) subunit alpha-1	polymer	352	40135.7	1	UniProt (P63096) In PDB	Homo sapiens (human)	Adenylate cyclase-inhibiting G alpha protein
3	B	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	340	37413.9	1	UniProt (P62873) In PDB	Homo sapiens (human)	Transducin beta chain 1
4	C	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	61	6795.9	1	UniProt (P59768) In PDB	Homo sapiens (human)	G gamma-I
5	E	scFv16	polymer	247	26337.3	1		Homo sapiens (human)
6	R	NICOTINIC ACID	non-polymer		123.1	1	Chemie (NIO)

Sequence modifications

A: 2 - 353 (UniProt: P63096)

PDB	External Database	Details
Asn 47	Ser 47	conflict
Ala 203	Gly 203	conflict
Ala 245	Glu 245	conflict
Ser 326	Ala 326	conflict

B: 2 - 340 (UniProt: P62873)

PDB	External Database	Details
Gln 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	152580.2
Non-Polymers*	Number of molecules	1
	Total formula weight	123.1
All*	Total formula weight	152703.3

*Water molecules are not included.