9IND
Integrin alpha-v beta-8 in complex with the Fab of 130H2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-V heavy chain | polymer | 440 | 47991.2 | 1 | UniProt (P06756) Pfam (PF01839) | Homo sapiens (human) | |
| 2 | B (H) | The heavy chain of 130H2-Fab | polymer | 119 | 13290.7 | 1 | Mus musculus | ||
| 3 | C (L) | The light chain of 130H2-Fab | polymer | 104 | 11332.6 | 1 | Mus musculus | ||
| 4 | D (B) | Integrin beta-8 | polymer | 352 | 39304.9 | 1 | UniProt (P26012) Pfam (PF00362) | Homo sapiens (human) | |
| 5 | E (C) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 6 | F, G, H, I (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A: 1 - 440 (UniProt: P06756)
| PDB | External Database | Details |
|---|---|---|
| Trp 419 | Tyr 449 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 111919.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 910.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 113715.0 |
