9IKQ
Crystal structure of OPTN LZD in complex with GTP-bound Rab8a(Q67L)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Ras-related protein Rab-8A | polymer | 181 | 20766.9 | 2 | UniProt (P61006) Pfam (PF00071) | Homo sapiens (human) | Oncogene c-mel |
| 2 | B, C (C, D) | Optineurin | polymer | 38 | 4326.9 | 2 | UniProt (Q96CV9) | Homo sapiens (human) | E3-14.7K-interacting protein,FIP-2,Huntingtin yeast partner L,Huntingtin-interacting protein 7,HIP-7,Huntingtin-interacting protein L,NEMO-related protein,Optic neuropathy-inducing protein,Transcription factor IIIA-interacting protein,TFIIIA-IntP |
| 3 | E, L (A, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 4 | F, Q (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, H, I, J, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | M, N, O, P (B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 7 | S, T, U, V (A, C, D, B) | water | water | 18.0 | 407 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 181 (UniProt: P61006)
| PDB | External Database | Details |
|---|---|---|
| Leu 67 | Gln 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 50187.6 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1835.8 | |
| All* | Total formula weight | 52023.4 |
