9IKQ
Crystal structure of OPTN LZD in complex with GTP-bound Rab8a(Q67L)
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00675 |
| Number of Residues | 14 |
| Details | SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKtcV |
| Chain | Residue | Details |
| A | LEU11-VAL24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:21378754, ECO:0000305|PubMed:27552051, ECO:0007744|PDB:3QBT, ECO:0007744|PDB:5SZI |
| Chain | Residue | Details |
| A | SER17 | |
| A | LYS153 | |
| B | SER17 | |
| B | GLY20 | |
| B | LYS21 | |
| B | CYS23 | |
| B | GLY66 | |
| B | ASN121 | |
| B | LYS122 | |
| B | ASP124 | |
| B | ALA152 | |
| A | GLY20 | |
| B | LYS153 | |
| A | LYS21 | |
| A | CYS23 | |
| A | GLY66 | |
| A | ASN121 | |
| A | LYS122 | |
| A | ASP124 | |
| A | ALA152 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:27552051, ECO:0007744|PDB:5SZI |
| Chain | Residue | Details |
| A | GLY18 | |
| A | VAL19 | |
| A | SER35 | |
| B | GLY18 | |
| B | VAL19 | |
| B | SER35 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21378754, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3QBT, ECO:0007744|PDB:5SZI |
| Chain | Residue | Details |
| A | THR22 | |
| A | THR40 | |
| B | THR22 | |
| B | THR40 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:21378754, ECO:0007744|PDB:3QBT |
| Chain | Residue | Details |
| A | SER39 | |
| B | SER39 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21378754, ECO:0007744|PDB:3QBT |
| Chain | Residue | Details |
| A | ASP63 | |
| B | ASP63 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by LRRK2 => ECO:0000269|PubMed:26824392, ECO:0000269|PubMed:29125462, ECO:0000269|PubMed:30209220, ECO:0000269|PubMed:30398148 |
| Chain | Residue | Details |
| A | THR72 | |
| B | THR72 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| A | SER181 | |
| B | SER181 |
