9II3
Cryo-EM Structure of the 2:1 Complex of mGlu3 and beta-arrestin1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (R, B) | Metabotropic glutamate receptor 3 | polymer | 879 | 99301.8 | 2 | UniProt (Q14832) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) | Homo sapiens (human) | mGluR3 |
| 2 | B (A) | Beta-arrestin-1 | polymer | 418 | 47067.3 | 1 | UniProt (P49407) Pfam (PF00339) Pfam (PF02752) | Homo sapiens (human) | Arrestin beta-1,Non-visual arrestin-2 |
| 3 | C (S) | scFv30 | polymer | 251 | 26986.7 | 1 | Mus musculus | ||
| 4 | E, F (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | G, I (R, B) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 6 | H, J (R, B) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) |
Sequence modifications
A: 1 - 418 (UniProt: P49407)
| PDB | External Database | Details |
|---|---|---|
| Val 59 | Cys 59 | conflict |
| Ser 125 | Cys 125 | conflict |
| Leu 140 | Cys 140 | conflict |
| Val 150 | Cys 150 | conflict |
| Glu 169 | Arg 169 | conflict |
| Val 242 | Cys 242 | conflict |
| Val 251 | Cys 251 | conflict |
| Ser 269 | Cys 269 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 272657.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1067.6 | |
| All* | Total formula weight | 274574.0 |
