9IGM

Structure of the 4-CHRD domain of human Chordin in complex with a Heparin Oligosaccharide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Chordin	polymer	501	53709.6	1	UniProt (Q9H2X0) Pfam (PF07452)	Homo sapiens (human)
2	B (X)	2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose	branched		1414.2	1	In PDB
3	C, D (A)	beta-D-mannopyranose	non-polymer		180.2	2	Chemie (BMA) PubChem (439680)
4	E, F, G, H (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG) PubChem (24139)
5	I, J, K (A)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA) PubChem (271)
6	L (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
7	M (A)	water	water		18.0	27	Chemie (HOH)

Sequence modifications

A: 168 - 652 (UniProt: Q9H2X0)

PDB	External Database	Details
Ala 164	-	expression tag
Pro 165	-	expression tag
Leu 166	-	expression tag
Ala 167	-	expression tag
Leu 630	Met 630	variant
Leu 653	-	expression tag
Val 654	-	expression tag
Pro 655	-	expression tag
Arg 656	-	expression tag
Gly 657	-	expression tag
Ser 658	-	expression tag
His 659	-	expression tag
His 660	-	expression tag
His 661	-	expression tag
His 662	-	expression tag
His 663	-	expression tag
His 664	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53709.6
Branched	Number of molecules	1
	Total formula weight	1414.2
Non-Polymers*	Number of molecules	10
	Total formula weight	1461.4
All*	Total formula weight	56585.3

*Water molecules are not included.