9I24
Coagulation factor Xa complex with a2-loop peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Activated factor Xa heavy chain | polymer | 254 | 28538.5 | 1 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (human) | |
| 2 | B (L) | Factor X light chain | polymer | 55 | 6034.8 | 1 | UniProt (P00742) Pfam (PF14670) | Homo sapiens (human) | |
| 3 | C (C) | Coagulation factor V heavy chain | polymer | 15 | 1866.8 | 1 | UniProt (P12259) | synthetic construct | |
| 4 | D (I) | GLU-GLY-ARG-chloromethyl ketone inhibitor (EGRCK) | polymer | 3 | 361.4 | 1 | synthetic construct | ||
| 5 | E (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | F (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | G (H) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | H (H) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 9 | I (H) | L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide | non-polymer | 395.9 | 1 | Chemie (0GJ) | |||
| 10 | J, M (C) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 11 | K (C) | ISOLEUCINE | non-polymer | 131.2 | 1 | Chemie (ILE) | |||
| 12 | L (C) | PHENYLALANINE | non-polymer | 165.2 | 1 | Chemie (PHE) | |||
| 13 | N (C) | O-PHOSPHOTYROSINE | non-polymer | 261.2 | 1 | Chemie (PTR) | |||
| 14 | O, P, Q, R (H, L, C, I) | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence modifications
H: 16 - 264 (UniProt: P00742)
L: 86 - 139 (UniProt: P00742)
| PDB | External Database | Details |
|---|---|---|
| Lys 243 | - | insertion |
| Thr 244 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Met 85 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 36801.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1415.3 | |
| All* | Total formula weight | 38216.8 |
