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9I0T

Crystal structure of TRIM25 PRYSPRY covalently bound to 2-chloro-1-[4-(3-methyl-4-phenyl-phenyl)carbonyl-1,4-diazepan-1-yl]ethanone

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin/ISG15 ligase TRIM25polymer19922695.21UniProt (Q14258)
Pfam (PF13765)
Pfam (PF00622)
Homo sapiens (human)Estrogen-responsive finger protein,RING finger protein 147,RING-type E3 ubiquitin transferase,RING-type E3 ubiquitin transferase TRIM25,Tripartite motif-containing protein 25,Ubiquitin/ISG15-conjugating enzyme TRIM25,Zinc finger protein 147
2B
(A)
1-[4-(3-methyl-4-phenyl-phenyl)carbonyl-1,4-diazepan-1-yl]ethanonenon-polymer336.41Chemie (A1IZK)
3C
(A)
waterwater18.084Chemie (HOH)
Sequence modifications
A: 1 - 196 (UniProt: Q14258)
PDBExternal DatabaseDetails
Gly -2-expression tag
Met -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight22695.2
Non-Polymers*Number of molecules1
Total formula weight336.4
All*Total formula weight23031.6
*Water molecules are not included.

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PDB entries from 2026-04-15

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