9I0B

E3 ubiquitin ligase CBL-B in complex with inhibitor

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	E3 ubiquitin-protein ligase CBL-B	polymer	394	45809.5	1	UniProt (Q13191) Pfam (PF02262) Pfam (PF02761) Pfam (PF02762) Pfam (PF00097)	Homo sapiens (human)
2	B (A)	3-[3-[3-methyl-1-(4-methyl-1,2,4-triazol-3-yl)cyclobutyl]phenyl]-5-(trifluoromethyl)-1~{H}-pyrazin-2-one	non-polymer		389.4	1	Chemie (A1IZF)
3	C, D (A)	ZINC ION	non-polymer		65.4	2	Chemie (ZN) PubChem (32051)
4	E (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA) PubChem (923)
5	F (A)	water	water		18.0	112	Chemie (HOH)

Sequence modifications

A: 36 - 427 (UniProt: Q13191)

PDB	External Database	Details
His 34	-	expression tag
Met 35	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45809.5
Non-Polymers*	Number of molecules	4
	Total formula weight	543.2
All*	Total formula weight	46352.7

*Water molecules are not included.