9HZL
High resolution cryo-EM structure of human complex III in mitochondria
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, L (A, N) | Cytochrome b-c1 complex subunit 8 | polymer | 82 | 9922.4 | 2 | UniProt (O14949) Pfam (PF02939) | Homo sapiens (human) | Complex III subunit 8,Complex III subunit VIII,Ubiquinol-cytochrome c reductase complex 9.5 kDa protein,Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C |
| 2 | B, C, M, N (B, C, O, P) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 274 | 29705.0 | 4 | UniProt (P47985) Pfam (PF09165) Pfam (PF02921) Pfam (PF00355) | Homo sapiens (human) | Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Rieske protein UQCRFS1,Ubiquinol-cytochrome c reductase iron-sulfur subunit |
| 3 | D, O (D, Q) | Cytochrome b-c1 complex subunit 9 | polymer | 63 | 7320.5 | 2 | UniProt (Q9UDW1) Pfam (PF05365) | Homo sapiens (human) | Complex III subunit 9,Complex III subunit X,Cytochrome c1 non-heme 7 kDa protein,Ubiquinol-cytochrome c reductase complex 7.2 kDa protein |
| 4 | E, P (E, R) | Cytochrome b-c1 complex subunit 6, mitochondrial | polymer | 91 | 10753.8 | 2 | UniProt (P07919) Pfam (PF02320) | Homo sapiens (human) | Complex III subunit 6,Complex III subunit VIII,Cytochrome c1 non-heme 11 kDa protein,Mitochondrial hinge protein,Ubiquinol-cytochrome c reductase complex 11 kDa protein |
| 5 | F, Q (F, S) | Cytochrome b-c1 complex subunit 7 | polymer | 111 | 13554.5 | 2 | UniProt (P14927) Pfam (PF02271) | Homo sapiens (human) | Complex III subunit 7,Complex III subunit VII,QP-C,Ubiquinol-cytochrome c reductase complex 14 kDa protein |
| 6 | G, R (G, T) | Cytochrome b-c1 complex subunit 10 | polymer | 56 | 6577.7 | 2 | UniProt (O14957) Pfam (PF08997) | Homo sapiens (human) | Complex III subunit 10,Complex III subunit XI,Ubiquinol-cytochrome c reductase complex 6.4 kDa protein |
| 7 | H, S (H, U) | Cytochrome c1, heme protein, mitochondrial | polymer | 325 | 35469.0 | 2 | UniProt (P08574) Pfam (PF02167) | Homo sapiens (human) | Complex III subunit 4,Complex III subunit IV,Cytochrome b-c1 complex subunit 4,Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit,Cytochrome c-1 |
| 8 | I, T (J, V) | Cytochrome b | polymer | 380 | 42745.3 | 2 | UniProt (P00156) Pfam (PF00033) Pfam (PF00032) | Homo sapiens (human) | Complex III subunit 3,Complex III subunit III,Cytochrome b-c1 complex subunit 3,Ubiquinol-cytochrome-c reductase complex cytochrome b subunit |
| 9 | J, U (K, W) | Cytochrome b-c1 complex subunit 2, mitochondrial | polymer | 453 | 48495.8 | 2 | UniProt (P22695) Pfam (PF00675) Pfam (PF05193) | Homo sapiens (human) | Complex III subunit 2,Core protein II,Ubiquinol-cytochrome-c reductase complex core protein 2 |
| 10 | K, V (L, Y) | Cytochrome b-c1 complex subunit 1, mitochondrial | polymer | 480 | 52704.7 | 2 | UniProt (P31930) Pfam (PF00675) Pfam (PF05193) | Homo sapiens (human) | Complex III subunit 1,Core protein I,Ubiquinol-cytochrome-c reductase complex core protein 1 |
| 11 | BA, DA, HA, KA, OA... (G, H, J, T, U...) | CARDIOLIPIN | non-polymer | 1464.0 | 9 | Chemie (CDL) PubChem (17753886) PubChem (5287898) | |||
| 12 | AB, LA, QA, X, XA... (Y, L, U, C, V) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 6 | Chemie (3PE) | |||
| 13 | MA, Y (P, C) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 14 | AA, PA (D, T) | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL | non-polymer | 767.1 | 2 | Chemie (PLX) PubChem (49867511) | |||
| 15 | CA, RA (H, U) | HEME C | non-polymer | 618.5 | 2 | Chemie (HEC) | |||
| 16 | EA, FA, TA, UA (J, V) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 17 | GA (J) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 1 | Chemie (PEE) PubChem (108229) PubChem (44891344) PubChem (54095275) PubChem (14238554) PubChem (5909904) PubChem (9546757) PubChem (6437392) PubChem (99655478) PubChem (99655479) PubChem (9546744) PubChem (138113035) PubChem (171729549) | |||
| 18 | IA, JA, VA, WA (J, V) | UBIQUINONE-10 | non-polymer | 863.3 | 4 | Chemie (U10) | |||
| 19 | NA (P) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 1 | Chemie (PC1) PubChem (65146) PubChem (94190) PubChem (10417837) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 22 |
| Total formula weight | 573907.0 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 28241.2 | |
| All* | Total formula weight | 602148.1 |
