9HVF
Native human PPP1R15B-P-eIF2-eIF2B complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Translation initiation factor eIF-2B subunit gamma | polymer | 452 | 50304.2 | 1 | UniProt (Q9NR50) Pfam (PF00483) Pfam (PF25084) | Homo sapiens (human) | eIF-2B GDP-GTP exchange factor subunit gamma |
| 2 | B (A) | Protein phosphatase 1 regulatory subunit 15B | polymer | 109 | 11927.3 | 1 | UniProt (Q5SWA1) | Homo sapiens (human) | |
| 3 | C (C) | Eukaryotic translation initiation factor 2 subunit 2 | polymer | 333 | 38454.5 | 1 | UniProt (P20042) Pfam (PF01873) | Homo sapiens (human) | Eukaryotic translation initiation factor 2 subunit beta,eIF-2-beta |
| 4 | D (D) | Eukaryotic translation initiation factor 2 subunit 3 | polymer | 472 | 51178.4 | 1 | UniProt (P41091) Pfam (PF00009) Pfam (PF03144) Pfam (PF09173) | Homo sapiens (human) | Eukaryotic translation initiation factor 2 subunit gamma X,eIF-2gX |
| 5 | E (B) | Eukaryotic translation initiation factor 2 subunit 1 | polymer | 315 | 36161.2 | 1 | UniProt (P05198) Pfam (PF00575) Pfam (PF07541) | Homo sapiens (human) | Eukaryotic translation initiation factor 2 subunit alpha,eIF-2alpha |
Sequence modifications
A: 411 - 511 (UniProt: Q5SWA1)
| PDB | External Database | Details |
|---|---|---|
| Asp 403 | - | expression tag |
| Tyr 404 | - | expression tag |
| Lys 405 | - | expression tag |
| Asp 406 | - | expression tag |
| Asp 407 | - | expression tag |
| Asp 408 | - | expression tag |
| Asp 409 | - | expression tag |
| Lys 410 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 188025.6 | |
| All* | Total formula weight | 188025.6 |
