9HQ5
Crystal structure of Tetraspanin CD63mutant Large Extracellular Loop (LEL) in complex with sybody SB3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CD63 antigen | polymer | 108 | 12430.1 | 1 | UniProt (P08962) | Homo sapiens (human) | Granulophysin,Lysosomal-associated membrane protein 3,LAMP-3,Lysosome integral membrane protein 1,Limp1,Melanoma-associated antigen ME491,OMA81H,Ocular melanoma-associated antigen,Tetraspanin-30,Tspan-30 |
| 2 | B (B) | Sybody SB3 | polymer | 144 | 15699.4 | 1 | synthetic construct | ||
| 3 | C, D, E (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) |
Sequence modifications
A: 104 - 203 (UniProt: P08962)
| PDB | External Database | Details |
|---|---|---|
| Arg 102 | - | expression tag |
| Ser 103 | - | expression tag |
| Ser 130 | Asn 130 | engineered mutation |
| Ser 150 | Asn 150 | engineered mutation |
| Ser 172 | Asn 172 | engineered mutation |
| Glu 204 | - | expression tag |
| Asn 205 | - | expression tag |
| Leu 206 | - | expression tag |
| Tyr 207 | - | expression tag |
| Phe 208 | - | expression tag |
| Gln 209 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28129.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 28417.7 |
