9HPE

The NTD dimer and the interfacing LBD region of the AMPAR complex GluA3- TARP gamma2 in the apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, C)	Isoform Flip of Glutamate receptor 3,Voltage-dependent calcium channel gamma-2 subunit	polymer	1179	132665.7	2	UniProt (P19492) UniProt (Q71RJ2)	Rattus norvegicus (Norway rat)	GluR-3,AMPA-selective glutamate receptor 3,GluR-C,GluR-K3,Glutamate receptor ionotropic,AMPA 3,Neuronal voltage-gated calcium channel gamma-2 subunit,Stargazin,Transmembrane AMPAR regulatory protein gamma-2,TARP gamma-2
2	C, D, E, F (B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
3	G (B)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

B, C: 2 - 843 (UniProt: P19492)

PDB	External Database	Details
Gly -7	-	expression tag
Asp -6	-	expression tag
Tyr -5	-	expression tag
Lys -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Asp 0	-	expression tag
Lys 1	-	expression tag
Gly 439	Arg 461	engineered mutation
Gly 844	-	linker
Gly 845	-	linker
Ser 846	-	linker
Gly 847	-	linker
Ser 848	-	linker
Gly 849	-	linker

B, C: 850 - 1171 (UniProt: Q71RJ2)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	265331.5
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	266216.3

*Water molecules are not included.