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9HOY

Variant P417G of Orotidine 5'-monophosphate decarboxylase-domain of human UMPS in complex with the product UMP at 1.2 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Uridine 5'-monophosphate synthasepolymer25828163.61UniProt (P11172)Homo sapiens (human)UMP synthase
2B
(A)
URIDINE-5'-MONOPHOSPHATEnon-polymer324.21Chemie (U5P)
PubChem (6030)
3C
(A)
waterwater18.0267Chemie (HOH)
Sequence modifications
A: 224 - 480 (UniProt: P11172)
PDBExternal DatabaseDetails
Met 223-initiating methionine
Gly 417Pro 417engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28163.6
Non-Polymers*Number of molecules1
Total formula weight324.2
All*Total formula weight28487.8
*Water molecules are not included.

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PDB entries from 2026-06-24

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