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9HM2

A swapped dimeric form of ZO1/TJP1 PDZ2 in complex with the C-terminal peptide from protein E of SARS-CoV-2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tight junction protein ZO-1polymer849348.72UniProt (Q07157)Homo sapiens (human)Tight junction protein 1,Zona occludens protein 1,Zonula occludens protein 1
2C, D
(C, D)
Envelope small membrane proteinpolymer121327.52UniProt (P0DTC4)Severe acute respiratory syndrome coronavirus 2E,sM protein
3E, F, G, H, I
(A, B)
IODIDE IONnon-polymer126.95Chemie (IOD)
4J, K, L, M
(A, B, C, D)
waterwater18.091Chemie (HOH)
Sequence modifications
A, B: 186 - 263 (UniProt: Q07157)
PDBExternal DatabaseDetails
Gly 184-expression tag
Ser 185-expression tag
Trp 264-expression tag
Asn 265-expression tag
Ser 266-expression tag
Ser 267-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight21352.3
Non-Polymers*Number of molecules5
Total formula weight634.5
All*Total formula weight21986.9
*Water molecules are not included.

243531

PDB entries from 2025-10-22

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