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9HLC

TRPML1 in complex with compound 11

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Mucolipin-1polymer62870518.54UniProt (Q9GZU1)
Pfam (PF21381)
Pfam (PF08016)
Homo sapiens (human)ML1,MG-2,Mucolipidin,Transient receptor potential channel mucolipin 1,TRPML1
2E, F, G, H
(E, F, G, H)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.44In PDB
GlyTouCan (G42666HT)
3GA, HA, I, J, R...
(D, A, B, C)
N-OCTANEnon-polymer114.28Chemie (OCT)
4AA, FA, IA, K, O...
(C, D, A, B)
DODECANEnon-polymer170.38Chemie (D12)
5BA, JA, L, U
(C, D, A, B)
(2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoatenon-polymer746.64Chemie (EUJ)
6CA, DA, M, V
(C, D, A, B)
(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-olnon-polymer286.44Chemie (A1IV5)
7EA, N, P, W
(D, A, B, C)
Octadecanenon-polymer254.54Chemie (8K6)
8KA, LA, MA, NA
(A, B, C, D)
waterwater18.0312Chemie (HOH)
Sequence modifications
A, B, C, D: 2 - 580 (UniProt: Q9GZU1)
PDBExternal DatabaseDetails
Met -47-initiating methionine
His -46-expression tag
His -45-expression tag
His -44-expression tag
His -43-expression tag
His -42-expression tag
His -41-expression tag
His -40-expression tag
His -39-expression tag
Gly -38-expression tag
Gly -37-expression tag
Ser -36-expression tag
Asp -35-expression tag
Tyr -34-expression tag
Lys -33-expression tag
Asp -32-expression tag
His -31-expression tag
Asp -30-expression tag
Gly -29-expression tag
Asp -28-expression tag
Tyr -27-expression tag
Lys -26-expression tag
Asp -25-expression tag
His -24-expression tag
Asp -23-expression tag
Ile -22-expression tag
Asp -21-expression tag
Tyr -20-expression tag
Lys -19-expression tag
Asp -18-expression tag
Asp -17-expression tag
Asp -16-expression tag
Asp -15-expression tag
Lys -14-expression tag
Gly -13-expression tag
Gly -12-expression tag
Ser -11-expression tag
Gly -10-expression tag
Gly -9-expression tag
Ser -8-expression tag
Glu -7-expression tag
Asn -6-expression tag
Leu -5-expression tag
Tyr -4-expression tag
Phe -3-expression tag
Gln -2-expression tag
Gly -1-expression tag
Pro 0-expression tag
Gly 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight282073.9
BranchedNumber of molecules4
Total formula weight1697.6
Non-Polymers*Number of molecules28
Total formula weight7426.4
All*Total formula weight291197.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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