9HIC

K166 acetylated human muscle pyruvate kinase, isoform M2 (PKM2), in complex with FBP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Pyruvate kinase PKM	polymer	537	58886.8	4	UniProt (P14618)	Homo sapiens (human)	Cytosolic thyroid hormone-binding protein,CTHBP,Opa-interacting protein 3,OIP-3,Pyruvate kinase 2/3,Pyruvate kinase muscle isozyme,Threonine-protein kinase PKM2,Thyroid hormone-binding protein 1,THBP1,Tumor M2-PK,Tyrosine-protein kinase PKM2,p58
2	E, G, I, K (A, B, C, D)	1,6-di-O-phosphono-beta-D-fructofuranose	non-polymer		340.1	4	Chemie (FBP)
3	F, H, J, L, M (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)
4	N, O, P, Q (A, B, C, D)	water	water		18.0	47	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 531 (UniProt: P14618)

PDB	External Database	Details
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	235547.1
Non-Polymers*	Number of molecules	9
	Total formula weight	1482.0
All*	Total formula weight	237029.1

*Water molecules are not included.