9HI7
Structure of MC.7.G5 T cell receptor in complex with MR1 R9H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, F) | Major histocompatibility complex class I-related gene protein | polymer | 290 | 33763.8 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B, F (B, G) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C, G (D, H) | T cell receptor alpha chain MC.7.G5 | polymer | 201 | 22690.2 | 2 | UniProt (P0DTU3) Pfam (PF07686) Pfam (PF09291) | Homo sapiens (human) | MC.7.G5 TRA,TR alpha chain TRAV38-2DV8*01J31*01C*01 |
| 4 | D, H (E, I) | T cell receptor beta chain MC.7.G5 | polymer | 248 | 28176.3 | 2 | UniProt (P0DTU4) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (human) | TR beta chain TRBV25-1*01J2S3*01C2*01,MC.7.G5 TRB |
| 5 | I, J (A, H) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, F: 1 - 270 (UniProt: Q95460)
B, G: 1 - 99 (UniProt: P61769)
D, H: 5 - 205 (UniProt: P0DTU3)
E, I: 0 - 247 (UniProt: P0DTU4)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| His 9 | Arg 31 | engineered mutation |
| Ser 261 | Cys 283 | conflict |
| Gly 271 | - | expression tag |
| Ser 272 | - | expression tag |
| Gly 273 | - | expression tag |
| Gly 274 | - | expression tag |
| Gly 275 | - | expression tag |
| Leu 276 | - | expression tag |
| Asn 277 | - | expression tag |
| Asp 278 | - | expression tag |
| Ile 279 | - | expression tag |
| Phe 280 | - | expression tag |
| Glu 281 | - | expression tag |
| Ala 282 | - | expression tag |
| Gln 283 | - | expression tag |
| Lys 284 | - | expression tag |
| Ile 285 | - | expression tag |
| Glu 286 | - | expression tag |
| Trp 287 | - | expression tag |
| His 288 | - | expression tag |
| Glu 289 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Cys 167 | Thr 182 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Cys 174 | Ser 193 | conflict |
| Ala 192 | Cys 211 | conflict |
| Asp 206 | Asn 225 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 193019.3 | |
| All* | Total formula weight | 193019.3 |
