9HFQ

Cryo-EM structure of human CDADC1 inactive mutant (E400A): trimer without a ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Cytidine and dCMP deaminase domain-containing protein 1	polymer	534	60652.3	3	UniProt (Q9BWV3) Pfam (PF00383)	Homo sapiens (human)	Cytidine deaminase,Testis development protein NYD-SP15
2	D, E, F, G, H... (A, B, C)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	J, K, L (A, B, C)	water	water		18.0	3	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 514 (UniProt: Q9BWV3)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ala 400	Glu 400	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	181957.0
Non-Polymers*	Number of molecules	6
	Total formula weight	392.5
All*	Total formula weight	182349.4

*Water molecules are not included.