9HEO

Open-state RyR1 in 0.05% POPC micelles, in complex with a nanobody and FKBP

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, G, J (A, C, G, J)	Ryanodine receptor 1	polymer	5027	564931.8	4	UniProt (P11716) Pfam (PF08709) Pfam (PF01365) Pfam (PF02026) Pfam (PF08454) Pfam (PF06459) Pfam (PF00520) Pfam (PF02815) Pfam (PF00622) Pfam (PF21119)	Oryctolagus cuniculus (rabbit)	RYR-1,RyR1,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor
2	B, D, H, K (B, D, H, K)	Nanobody 9657	polymer	126	13783.1	4		Lama glama
3	E, F, I, L (E, F, I, L)	Peptidyl-prolyl cis-trans isomerase FKBP1B	polymer	107	11667.3	4	UniProt (Q8HYX6) Pfam (PF00254)	Oryctolagus cuniculus (rabbit)	PPIase FKBP1B,12.6 kDa FK506-binding protein,12.6 kDa FKBP,FKBP-12.6,FK506-binding protein 1B,FKBP-1B,Immunophilin FKBP12.6,Rotamase
4	HB, HC, LA, M (G, J, C, A)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5	IB, IC, MA, N (G, J, C, A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	4	Chemie (ATP)
6	JB, JC, NA, O (G, J, C, A)	CAFFEINE	non-polymer		194.2	4	Chemie (CFF)
7	KB, KC, OA, P (G, J, C, A)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
8	AA, AB, AC, BA, BB... (A, C, J, G)	(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate	non-polymer		760.1	72	Chemie (POV)

Sequence modifications

E, F, I, L: 1 - 107 (UniProt: Q8HYX6)

PDB	External Database	Details
Asp 100	Gly 101	conflict

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	2361528.7
Non-Polymers*	Number of molecules	88
	Total formula weight	57952.9
All*	Total formula weight	2419481.6

*Water molecules are not included.