9HCO
Outward-open structure of human serotonin transporter bound to vilazodone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium-dependent serotonin transporter | polymer | 685 | 76116.5 | 1 | UniProt (P31645) Pfam (PF03491) Pfam (PF00209) | Homo sapiens (human) | SERT,5HT transporter,5HTT,Solute carrier family 6 member 4 |
| 2 | B (H) | 15B8 Fab heavy chain | polymer | 229 | 24516.5 | 1 | Mus musculus | ||
| 3 | C (L) | 15B8 Fab light chain | polymer | 216 | 23559.0 | 1 | Mus musculus | ||
| 4 | D (A) | 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide | non-polymer | 441.5 | 1 | Chemie (YG7) | |||
| 5 | E, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 6 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 7 | H, I (A, H) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 1 - 630 (UniProt: P31645)
| PDB | External Database | Details |
|---|---|---|
| Gly 631 | - | expression tag |
| Gly 632 | - | expression tag |
| Ser 633 | - | expression tag |
| Leu 634 | - | expression tag |
| Val 635 | - | expression tag |
| Pro 636 | - | expression tag |
| Arg 637 | - | expression tag |
| Gly 638 | - | expression tag |
| Ser 639 | - | expression tag |
| Gly 640 | - | expression tag |
| Gly 641 | - | expression tag |
| Ser 642 | - | expression tag |
| Trp 643 | - | expression tag |
| Ser 644 | - | expression tag |
| His 645 | - | expression tag |
| Pro 646 | - | expression tag |
| Gln 647 | - | expression tag |
| Phe 648 | - | expression tag |
| Glu 649 | - | expression tag |
| Lys 650 | - | expression tag |
| Gly 651 | - | expression tag |
| Gly 652 | - | expression tag |
| Gly 653 | - | expression tag |
| Ser 654 | - | expression tag |
| Gly 655 | - | expression tag |
| Gly 656 | - | expression tag |
| Gly 657 | - | expression tag |
| Ser 658 | - | expression tag |
| Gly 659 | - | expression tag |
| Gly 660 | - | expression tag |
| Ser 661 | - | expression tag |
| Ala 662 | - | expression tag |
| Trp 663 | - | expression tag |
| Ser 664 | - | expression tag |
| His 665 | - | expression tag |
| Pro 666 | - | expression tag |
| Gln 667 | - | expression tag |
| Phe 668 | - | expression tag |
| Glu 669 | - | expression tag |
| Lys 670 | - | expression tag |
| Gly 671 | - | expression tag |
| Gly 672 | - | expression tag |
| Ser 673 | - | expression tag |
| His 674 | - | expression tag |
| His 675 | - | expression tag |
| His 676 | - | expression tag |
| His 677 | - | expression tag |
| His 678 | - | expression tag |
| His 679 | - | expression tag |
| His 680 | - | expression tag |
| His 681 | - | expression tag |
| His 682 | - | expression tag |
| His 683 | - | expression tag |
| His 684 | - | expression tag |
| His 685 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 124191.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 523.0 | |
| All* | Total formula weight | 124714.9 |
