9HAQ
Crystal structure of methionine gamma-lyase from Brevibacterium sandarakinum in complex with PLP and norleucine at pH 8.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, F, H... (A, B, D, F, H...) | Cystathionine gamma-synthase | polymer | 413 | 43131.6 | 9 | UniProt (A0A1H1YBL2) Pfam (PF01053) | Brevibacterium sandarakinum | Methionine gamma-lyase (MGL) |
| 2 | C, E, G, K, M... (C, E, G, K, M...) | Cystathionine gamma-synthase | polymer | 413 | 42903.5 | 7 | UniProt (A0A1H1YBL2) Pfam (PF01053) | Brevibacterium sandarakinum | Methionine gamma-lyase (MGL) |
| 3 | BA, Q, R, T, W (J, A, B, D, F) | NORLEUCINE | non-polymer | 131.2 | 5 | Chemie (NLE) | |||
| 4 | AA, DA, EA, FA, GA... (I, K, M, N, O...) | 2-[O-PHOSPHONOPYRIDOXYL]-AMINO-HEXANOIC ACID | non-polymer | 362.3 | 10 | Chemie (PY6) | |||
| 5 | CA, U, X (J, D, F) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | HA (P) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 7 | JA, KA, LA, MA, NA... (A, B, C, D, E...) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A, B, D, F, H, I, J, L, P: 1 - 393 (UniProt: A0A1H1YBL2)
C, E, G, K, M, N, O: 1 - 393 (UniProt: A0A1H1YBL2)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 688508.4 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 4844.5 | |
| All* | Total formula weight | 693352.9 |
