9GZV
Crystal structure of human NUDT14 in complex with a potent inhibitor (MA-955-9)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Uridine diphosphate glucose pyrophosphatase NUDT14 | polymer | 223 | 24228.3 | 2 | UniProt (O95848) | Homo sapiens (human) | UDPG pyrophosphatase,UGPPase,Nucleoside diphosphate-linked moiety X motif 14,Nudix motif 14 |
| 2 | C, H, L (A, B) | 1-(1-methylpiperidin-4-yl)-3-(3-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine | non-polymer | 400.5 | 3 | Chemie (A1IRF) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E, N (A, B) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 5 | F, G, M (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | I (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | J, K, O (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 8 | P, Q (A, B) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 222 (UniProt: O95848)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48456.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1990.7 | |
| All* | Total formula weight | 50447.3 |
