9GVO

type-I interferons autoantibodies pmab15 and pmab14 in complex with Interferon alpha-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	scFv type-I interferons autoantibody pmab14	polymer	290	30180.0	1		Homo sapiens
2	B (B)	Interferon alpha-2	polymer	188	21581.5	1	UniProt (P01563) Pfam (PF00143)	Homo sapiens (human)	IFN-alpha-2,Interferon alpha-A,LeIF A
3	C (H)	scFv type-I interferons autoantibody pmab15	polymer	294	30802.3	1		Homo sapiens
4	D, E, F, G, H... (A, B, H)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
5	I, L (B, H)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
6	J (B)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
7	M, N, O (A, B, H)	water	water		18.0	384	Chemie (HOH)

Sequence modifications

B: 1 - 165 (UniProt: P01563)

PDB	External Database	Details
Gly 166	-	expression tag
Gly 167	-	expression tag
Gly 168	-	expression tag
Gly 169	-	expression tag
Ser 170	-	expression tag
Leu 171	-	expression tag
Val 172	-	expression tag
Pro 173	-	expression tag
Arg 174	-	expression tag
Gly 175	-	expression tag
Ser 176	-	expression tag
Gly 177	-	expression tag
Gly 178	-	expression tag
Gly 179	-	expression tag
Ser 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	82563.8
Non-Polymers*	Number of molecules	9
	Total formula weight	781.6
All*	Total formula weight	83345.4

*Water molecules are not included.