9GRO
Crystal structure of the engineered C-terminal phosphatase domain from Saccharomyces cerevisiae Vip1 in complex with 1,5-InsP8 (phosphatase dead mutant, loop deletion residues 848-918)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase | polymer | 507 | 58346.4 | 2 | UniProt (Q06685) Pfam (PF00328) | Saccharomyces cerevisiae (brewer's yeast) | InsP6 and PP-IP5 kinase |
| 2 | C, U (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E (A) | SPERMINE | non-polymer | 202.3 | 2 | Chemie (SPM) | |||
| 4 | F (A) | L-ornithine | non-polymer | 132.2 | 1 | Chemie (ORN) | |||
| 5 | BA, G, H, N, T... (B, A) | 1,4-DIAMINOBUTANE | non-polymer | 88.2 | 6 | Chemie (PUT) | |||
| 6 | AA, CA, EA, FA, I... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 15 | Chemie (EDO) | |||
| 7 | DA, Q (B, A) | (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)] | non-polymer | 820.0 | 2 | Chemie (I8P) | |||
| 8 | V, X (B) | (2S)-hexane-1,2,6-triol | non-polymer | 134.2 | 2 | Chemie (1JW) | |||
| 9 | GA, HA (A, B) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A, B: 536 - 1107 (UniProt: Q06685)
| PDB | External Database | Details |
|---|---|---|
| Gly 534 | - | expression tag |
| Ala 535 | - | expression tag |
| Ala 547 | Arg 547 | conflict |
| Ala 548 | His 548 | conflict |
| Ala 551 | Arg 551 | conflict |
| - | Leu 849 | deletion |
| - | Pro 850 | deletion |
| - | Asn 851 | deletion |
| - | Glu 852 | deletion |
| - | Ala 853 | deletion |
| - | Ile 854 | deletion |
| - | Ala 855 | deletion |
| - | Asp 856 | deletion |
| - | Glu 857 | deletion |
| - | Leu 858 | deletion |
| - | Gly 859 | deletion |
| - | Ser 860 | deletion |
| - | His 861 | deletion |
| - | Ser 862 | deletion |
| - | Leu 863 | deletion |
| - | Val 864 | deletion |
| - | Asp 865 | deletion |
| - | Arg 866 | deletion |
| - | Tyr 867 | deletion |
| - | Pro 868 | deletion |
| - | Ile 869 | deletion |
| - | Asn 870 | deletion |
| - | Val 871 | deletion |
| - | Leu 872 | deletion |
| - | Ala 873 | deletion |
| - | Lys 874 | deletion |
| - | Asn 875 | deletion |
| - | Asn 876 | deletion |
| - | Phe 877 | deletion |
| - | Lys 878 | deletion |
| - | Ile 879 | deletion |
| - | Ile 880 | deletion |
| - | Asp 881 | deletion |
| - | Ser 882 | deletion |
| - | His 883 | deletion |
| - | Ser 884 | deletion |
| - | Met 885 | deletion |
| - | Asn 886 | deletion |
| - | Asn 887 | deletion |
| - | Ser 888 | deletion |
| - | Gly 889 | deletion |
| - | Lys 890 | deletion |
| - | Asn 891 | deletion |
| - | Ser 892 | deletion |
| - | Ser 893 | deletion |
| - | Asn 894 | deletion |
| - | Ser 895 | deletion |
| - | Val 896 | deletion |
| - | Gly 897 | deletion |
| - | Ser 898 | deletion |
| - | Leu 899 | deletion |
| - | Gly 900 | deletion |
| - | Trp 901 | deletion |
| - | Val 902 | deletion |
| - | Leu 903 | deletion |
| - | Glu 904 | deletion |
| - | Ser 905 | deletion |
| - | Gly 906 | deletion |
| - | Lys 907 | deletion |
| - | Thr 908 | deletion |
| - | Ser 909 | deletion |
| - | Thr 910 | deletion |
| - | Ala 911 | deletion |
| - | Arg 912 | deletion |
| - | Asn 913 | deletion |
| - | Pro 914 | deletion |
| - | Lys 915 | deletion |
| Gly 918 | Ser 918 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116692.7 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 4035.9 | |
| All* | Total formula weight | 120728.6 |
