9GP4
Jumonji domain-containing protein 2A with crystallization epitope mutations Q953E:A958D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific demethylase 4A | polymer | 117 | 13306.6 | 1 | UniProt (O75164) Pfam (PF18104) | Homo sapiens (human) | JmjC domain-containing histone demethylation protein 3A,Jumonji domain-containing protein 2A,[histone H3]-trimethyl-L-lysine(36) demethylase 4A,[histone H3]-trimethyl-L-lysine(9) demethylase 4A |
| 2 | B, C, D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 3 | G, H (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | I (A) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A: 3 - 117 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Met 2 | - | expression tag |
| Ala 19 | Arg 913 | conflict |
| Glu 59 | Gln 953 | engineered mutation |
| Asp 64 | Ala 958 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13306.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 502.5 | |
| All* | Total formula weight | 13809.0 |
