9GP1
Jumonji domain-containing protein 2A with crystallization epitope mutatios K330R:A334E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Lysine-specific demethylase 4A | polymer | 360 | 41940.7 | 4 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | Homo sapiens (human) | JmjC domain-containing histone demethylation protein 3A,Jumonji domain-containing protein 2A,[histone H3]-trimethyl-L-lysine(36) demethylase 4A,[histone H3]-trimethyl-L-lysine(9) demethylase 4A |
| 2 | E, G, I, K (A, B, C, D) | NICKEL (II) ION | non-polymer | 58.7 | 4 | Chemie (NI) | |||
| 3 | F, H, J, L (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 537 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 360 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Arg 331 | Lys 330 | engineered mutation |
| Glu 335 | Ala 334 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 167762.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 496.4 | |
| All* | Total formula weight | 168259.1 |
