9GLZ
KRas-G12D-GMPPnP in complex with the nanobody KM12-AM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GTPase KRas | polymer | 170 | 19364.7 | 2 | UniProt (A0A7K5XXT4) Pfam (PF00071) | Homo sapiens (human) | Ki-Ras |
| 2 | C, D (C, D) | nanobody KM12-AM | polymer | 135 | 14775.2 | 2 | Homo sapiens | ||
| 3 | E, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, H (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 169 (UniProt: A0A7K5XXT4)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Asp 12 | Gly 12 | engineered mutation |
| Ser 51 | Cys 51 | engineered mutation |
| Leu 80 | Cys 80 | engineered mutation |
| Ser 118 | Cys 118 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 68279.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1093.0 | |
| All* | Total formula weight | 69372.9 |
