9GLE
Jumonji domain-containing protein 2A with crystallization epitope mutations A91T:T93S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lysine-specific demethylase 4A | polymer | 360 | 41870.6 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | Homo sapiens (human) | JmjC domain-containing histone demethylation protein 3A,Jumonji domain-containing protein 2A,[histone H3]-trimethyl-L-lysine(36) demethylase 4A,[histone H3]-trimethyl-L-lysine(9) demethylase 4A |
| 2 | C, M (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 3 | D, E, F, N, O (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | G, P (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | H, I, J, K, L... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | R, S (A, B) | water | water | 18.0 | 446 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 360 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Thr 92 | Ala 91 | engineered mutation |
| Ser 94 | Thr 93 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83741.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1100.9 | |
| All* | Total formula weight | 84842.2 |
