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9GL9

Wild-type EGFR bound with STX-721

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Epidermal growth factor receptorpolymer33037563.51UniProt (P00533)
Pfam (PF07714)
Homo sapiens (human)Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1
2B, C
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
3D
(A)
(2R,3S)-3-[(3-chloranyl-2-methoxy-phenyl)amino]-2-[3-[2-[(2R)-1-[(E)-4-(dimethylamino)but-2-enoyl]-2-methyl-pyrrolidin-2-yl]ethynyl]pyridin-4-yl]-1,2,3,5,6,7-hexahydropyrrolo[3,2-c]pyridin-4-onenon-polymer589.11Chemie (A1IMT)
4E
(A)
waterwater18.0212Chemie (HOH)
Sequence modifications
A: 696 - 1022 (UniProt: P00533)
PDBExternal DatabaseDetails
Gly 693-expression tag
Ala 694-expression tag
Met 695-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37563.5
Non-Polymers*Number of molecules3
Total formula weight660.0
All*Total formula weight38223.5
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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