9GKV

Crystal Structure of Deacetylase (HdaH) from Vibrio cholerae in complex with SAHA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Histone deacetylase	polymer	318	35291.1	2	UniProt (A0A395TF31) Pfam (PF00850)	Vibrio cholerae
2	C (B)	OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE	non-polymer		264.3	1	Chemie (SHH)
3	D, K (B, A)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	E, F, G, H, L... (B, A)	POTASSIUM ION	non-polymer		39.1	8	Chemie (K)
5	I, J (A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
6	P, Q (B, A)	water	water		18.0	363	Chemie (HOH)

Sequence modifications

B, A: 12 - 318 (UniProt: A0A395TF31)

PDB	External Database	Details
Met 1	-	initiating methionine
Ala 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Val 9	-	expression tag
Gly 10	-	expression tag
Thr 11	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70582.2
Non-Polymers*	Number of molecules	13
	Total formula weight	826.0
All*	Total formula weight	71408.2

*Water molecules are not included.