9GHJ
Junin virus GP1-GP2 heterodimer in complex with Fab of JUN1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Pre-glycoprotein polyprotein GP complex | polymer | 193 | 22401.7 | 1 | UniProt (C1K9J9) | Mammarenavirus juninense | Pre-GP-C |
| 2 | B (B) | Glycoprotein G2 | polymer | 203 | 22924.7 | 1 | UniProt (P26313) | Mammarenavirus juninense | GP2 |
| 3 | C (H) | JUN1 heavy chain | polymer | 242 | 26402.5 | 1 | Mus musculus | ||
| 4 | D (L) | JUN1 light chain | polymer | 217 | 23943.5 | 1 | Mus musculus | ||
| 5 | E (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 6 | F (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 7 | G (E) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 8 | H, I (F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 9 | J (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 10 | K, L, M, N (A, B, H, L) | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A: 59 - 251 (UniProt: C1K9J9)
B: 252 - 416 (UniProt: P26313)
| PDB | External Database | Details |
|---|---|---|
| Cys 88 | Leu 88 | engineered mutation |
| Arg 249 | Ser 249 | engineered mutation |
| Arg 250 | Leu 250 | engineered mutation |
| Arg 251 | Lys 251 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Pro 321 | Glu 321 | engineered mutation |
| Cys 329 | Met 329 | engineered mutation |
| Ser 417 | - | expression tag |
| Gly 418 | - | expression tag |
| Asp 419 | - | expression tag |
| Asp 420 | - | expression tag |
| Asp 421 | - | expression tag |
| Asp 422 | - | expression tag |
| Lys 423 | - | expression tag |
| Gly 424 | - | expression tag |
| Ser 425 | - | expression tag |
| Gly 426 | - | expression tag |
| Trp 427 | - | expression tag |
| Ser 428 | - | expression tag |
| His 429 | - | expression tag |
| Pro 430 | - | expression tag |
| Gln 431 | - | expression tag |
| Phe 432 | - | expression tag |
| Glu 433 | - | expression tag |
| Lys 434 | - | expression tag |
| Gly 435 | - | expression tag |
| Gly 436 | - | expression tag |
| Gly 437 | - | expression tag |
| Ser 438 | - | expression tag |
| Gly 439 | - | expression tag |
| Gly 440 | - | expression tag |
| Gly 441 | - | expression tag |
| Ser 442 | - | expression tag |
| Gly 443 | - | expression tag |
| Gly 444 | - | expression tag |
| Ser 445 | - | expression tag |
| Ala 446 | - | expression tag |
| Trp 447 | - | expression tag |
| Ser 448 | - | expression tag |
| His 449 | - | expression tag |
| Pro 450 | - | expression tag |
| Gln 451 | - | expression tag |
| Phe 452 | - | expression tag |
| Glu 453 | - | expression tag |
| Lys 454 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 95672.3 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2900.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 150.2 | |
| All* | Total formula weight | 98723.2 |
