9GGW

Human KRas4A (GDP) in complex with compound 16

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GTPase KRas	polymer	172	19607.1	2	UniProt (P01116) Pfam (PF00071)	Homo sapiens (human)	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2	C, G (A, B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
3	D, H (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	E, I (A, B)	11-(4-aminocyclohexyl)-16-chloro-1,15-dihydroxy-10,10-dioxo-10lambda6-thia-2,11lambda6-diaza-1lambda6,15lambda6-diphospha-3-phosphoniapentacyclo[7.5.1.01,15.03,15.013,15]hexadecan-12-one	non-polymer		566.1	2	Chemie (A1ILA)
5	F, J (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	K, L (A, B)	water	water		18.0	130	Chemie (HOH)

Sequence modifications

A, B: 1 - 169 (UniProt: P01116)

PDB	External Database	Details
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ser 118	Cys 118	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	39214.2
Non-Polymers*	Number of molecules	8
	Total formula weight	2191.4
All*	Total formula weight	41405.5

*Water molecules are not included.