9GG5
Cryo-EM structure of Thromboxane A2 receptor-miniGq protein complex bound to U46619
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Thromboxane A2 receptor | polymer | 343 | 37463.0 | 1 | UniProt (P21731) Pfam (PF00001) | Homo sapiens (human) | TXA2-R,Prostanoid TP receptor |
| 2 | B (A) | Engineered miniGq | polymer | 246 | 28084.8 | 1 | Homo sapiens | ||
| 3 | C (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 4 | D (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 5 | E (R) | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid | non-polymer | 350.5 | 1 | Chemie (PUC) | |||
| 6 | F, G, H, I (R) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110825.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1897.1 | |
| All* | Total formula weight | 112723.0 |
