9GEW
Crystal structure of CREBBP bromodomain in complex with (R,E)-6-(5-(6-methoxy-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)pent-1-en-1-yl)-4-methyl-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CREBBP | polymer | 119 | 14223.3 | 1 | UniProt (Q92793) Pfam (PF00439) | Homo sapiens (human) | |
| 2 | B (A) | (4~{R})-6-[(~{E})-5-(6-methoxy-2,3-dihydro-1,4-benzoxazin-4-yl)pent-1-enyl]-4-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one | non-polymer | 407.5 | 1 | Chemie (A1IKI) | |||
| 3 | C, D, E (A) | (R,R)-2,3-BUTANEDIOL | non-polymer | 90.1 | 3 | Chemie (BU3) | |||
| 4 | F (A) | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14223.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 677.9 | |
| All* | Total formula weight | 14901.2 |
