9GCH
Human mitochondrial RNase Z with tRNA-His-CCA, SDR5C1/TRMT10C focus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3-hydroxyacyl-CoA dehydrogenase type-2 | polymer | 261 | 26947.0 | 4 | UniProt (Q99714) Pfam (PF00106) | Homo sapiens (human) | 17-beta-estradiol 17-dehydrogenase,2-methyl-3-hydroxybutyryl-CoA dehydrogenase,MHBD,3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)),3-hydroxy-2-methylbutyryl-CoA dehydrogenase,3-hydroxyacyl-CoA dehydrogenase type II,3alpha(or 20beta)-hydroxysteroid dehydrogenase,7-alpha-hydroxysteroid dehydrogenase,Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,Mitochondrial ribonuclease P protein 2,Mitochondrial RNase P protein 2,Short chain dehydrogenase/reductase family 5C member 1,Short-chain type dehydrogenase/reductase XH98G2,Type II HADH |
| 2 | E (F) | tRNA methyltransferase 10 homolog C | polymer | 356 | 42055.3 | 1 | UniProt (Q7L0Y3) Pfam (PF01746) | Homo sapiens (human) | HBV pre-S2 trans-regulated protein 2,Mitochondrial ribonuclease P protein 1,Mitochondrial RNase P protein 1,RNA (guanine-9-)-methyltransferase domain-containing protein 1,Renal carcinoma antigen NY-REN-49,mRNA methyladenosine-N(1)-methyltransferase,tRNA (adenine(9)-N(1))-methyltransferase,tRNA (guanine(9)-N(1))-methyltransferase |
| 3 | F (T) | mt-tRNA-His-CCA | polymer | 71 | 22626.5 | 1 | GenBank (1896813685) | Homo sapiens | |
| 4 | G (F) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 5 | H (T) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 6 | I (T) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | J, K (F, T) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
F: 70 - 403 (UniProt: Q7L0Y3)
| PDB | External Database | Details |
|---|---|---|
| Ala 404 | - | expression tag |
| Glu 405 | - | expression tag |
| Asn 406 | - | expression tag |
| Leu 407 | - | expression tag |
| Tyr 408 | - | expression tag |
| Phe 409 | - | expression tag |
| Gln 410 | - | expression tag |
| Ser 411 | - | expression tag |
| His 412 | - | expression tag |
| His 413 | - | expression tag |
| His 414 | - | expression tag |
| His 415 | - | expression tag |
| His 416 | - | expression tag |
| His 417 | - | expression tag |
| Asp 418 | - | expression tag |
| Tyr 419 | - | expression tag |
| Lys 420 | - | expression tag |
| Asp 421 | - | expression tag |
| Asp 422 | - | expression tag |
| Asp 423 | - | expression tag |
| Asp 424 | - | expression tag |
| Lys 425 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 172469.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 945.9 | |
| All* | Total formula weight | 173415.8 |
