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9G0U

Human LTC4 synthase in complex with AZD9898

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Leukotriene C4 synthasepolymer15717468.61UniProt (Q16873)
Pfam (PF01124)
Homo sapiens (human)LTC4 synthase,Glutathione S-transferase LTC4,Leukotriene-C(4) synthase,Leukotriene-C4 synthase
2B
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3C, E, F, G, H...
(A)
PALMITIC ACIDnon-polymer256.410Chemie (PLM)
4D, J, K, L, M...
(A)
PALMITOLEIC ACIDnon-polymer254.48Chemie (PAM)
5R
(A)
DODECYL-BETA-D-MALTOSIDEnon-polymer510.61Chemie (LMT)
6V
(A)
(1~{S},2~{S})-2-[5-[[5-chloranyl-2,4-bis(fluoranyl)phenyl]-(2-fluoranyl-2-methyl-propyl)amino]-3-methoxy-pyrazin-2-yl]carbonylcyclopropane-1-carboxylic acidnon-polymer457.81Chemie (A1IHJ)
7W
(A)
waterwater18.026Chemie (HOH)
Sequence modifications
A: 2 - 150 (UniProt: Q16873)
PDBExternal DatabaseDetails
Met -6-initiating methionine
His -5-expression tag
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
His 0-expression tag
Gly 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17468.6
Non-Polymers*Number of molecules21
Total formula weight5664.0
All*Total formula weight23132.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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