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9FWH

Crystal Structure of SARS-CoV-2 NSP10-ExoN in complex with VT00019

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Non-structural protein 10polymer13113805.71UniProt (P0DTC1)
Pfam (PF09401)
Severe acute respiratory syndrome coronavirus 2nsp10,Growth factor-like peptide,GFL
2B
(B)
Guanine-N7 methyltransferase nsp14polymer29032753.81UniProt (P0DTD1)
Pfam (PF06471)
Severe acute respiratory syndrome coronavirus 2Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN
3C, D, F, G
(A, B)
ZINC IONnon-polymer65.44Chemie (ZN)
4E
(B)
(4R)-4-phenyl-1,2-thiazolidine 1,1-dioxidenon-polymer197.31Chemie (A1IGQ)
5H, I
(A, B)
waterwater18.089Chemie (HOH)
Sequence modifications
A: 1 - 130 (UniProt: P0DTC1)
PDBExternal DatabaseDetails
Asp 131-expression tag
B: 1 - 289 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Met 0-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight46559.5
Non-Polymers*Number of molecules5
Total formula weight458.9
All*Total formula weight47018.4
*Water molecules are not included.

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PDB entries from 2025-07-23

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