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9FRD

Wildtype EGFR bound with Compound 23

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Epidermal growth factor receptorpolymer33037579.51UniProt (P00533)
Pfam (PF07714)
Homo sapiens (human)Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1
2B
(A)
2,3-DIHYDROXY-1,4-DITHIOBUTANEnon-polymer154.31Chemie (DTT)
3C
(A)
(7~{S})-3-[(3-chloranyl-2-methoxy-phenyl)amino]-2-(3-fluoranylpyridin-4-yl)-7-(2-methoxyethyl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-onenon-polymer444.91Chemie (A1IEZ)
4D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5E
(A)
waterwater18.0128Chemie (HOH)
Sequence modifications
A: 696 - 1022 (UniProt: P00533)
PDBExternal DatabaseDetails
Gly 693-expression tag
Ser 694-expression tag
Met 695-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37579.5
Non-Polymers*Number of molecules3
Total formula weight634.6
All*Total formula weight38214.0
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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