9FQW
Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the ornithine-bound inward-occluded state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity cationic amino acid transporter 1,Green fluorescent protein | polymer | 902 | 98703.8 | 1 | UniProt (Q09143) UniProt (P42212) | Mus musculus (house mouse) | CAT-1,CAT1,Ecotropic retroviral leukemia receptor,Ecotropic retrovirus receptor,ERR,EcoR,Solute carrier family 7 member 1,System Y+ basic amino acid transporter |
| 2 | B (B) | Surface protein | polymer | 276 | 30272.1 | 1 | UniProt (P03390) | Murine leukemia virus | SU,Glycoprotein 70,gp70 |
| 3 | C (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G42466VF) | |||
| 4 | D (I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F, G (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) | |||
| 7 | H (A) | L-ornithine | non-polymer | 132.2 | 1 | Chemie (ORN) |
Sequence modifications
A: 13 - 622 (UniProt: Q09143)
A: 635 - 871 (UniProt: P42212)
B: 35 - 270 (UniProt: P03390)
| PDB | External Database | Details |
|---|---|---|
| Ala 623 | - | linker |
| Glu 624 | - | linker |
| Asn 625 | - | linker |
| Leu 626 | - | linker |
| Tyr 627 | - | linker |
| Phe 628 | - | linker |
| Gln 629 | - | linker |
| Ser 630 | - | linker |
| Gly 631 | - | linker |
| Ser 632 | - | linker |
| Ala 633 | - | linker |
| Val 634 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 697 | Phe 64 | conflict |
| Thr 698 | Ser 65 | conflict |
| Lys 839 | Ala 206 | conflict |
| Leu 864 | His 231 | conflict |
| Ser 872 | - | expression tag |
| Gly 873 | - | expression tag |
| Leu 874 | - | expression tag |
| Arg 875 | - | expression tag |
| Ser 876 | - | expression tag |
| Trp 877 | - | expression tag |
| Ser 878 | - | expression tag |
| His 879 | - | expression tag |
| Pro 880 | - | expression tag |
| Gln 881 | - | expression tag |
| Phe 882 | - | expression tag |
| Glu 883 | - | expression tag |
| Lys 884 | - | expression tag |
| Gly 885 | - | expression tag |
| Gly 886 | - | expression tag |
| Gly 887 | - | expression tag |
| Ser 888 | - | expression tag |
| Gly 889 | - | expression tag |
| Gly 890 | - | expression tag |
| Gly 891 | - | expression tag |
| Ser 892 | - | expression tag |
| Gly 893 | - | expression tag |
| Gly 894 | - | expression tag |
| Ser 895 | - | expression tag |
| Ala 896 | - | expression tag |
| Trp 897 | - | expression tag |
| Ser 898 | - | expression tag |
| His 899 | - | expression tag |
| Pro 900 | - | expression tag |
| Gln 901 | - | expression tag |
| Phe 902 | - | expression tag |
| Glu 903 | - | expression tag |
| Lys 904 | - | expression tag |
| His 905 | - | expression tag |
| His 906 | - | expression tag |
| His 907 | - | expression tag |
| His 908 | - | expression tag |
| His 909 | - | expression tag |
| His 910 | - | expression tag |
| His 911 | - | expression tag |
| His 912 | - | expression tag |
| His 913 | - | expression tag |
| His 914 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 4 | - | initiating methionine |
| Gly 5 | - | expression tag |
| Ile 6 | - | expression tag |
| Leu 7 | - | expression tag |
| Pro 8 | - | expression tag |
| Ser 9 | - | expression tag |
| Pro 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Met 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Ala 14 | - | expression tag |
| Leu 15 | - | expression tag |
| Leu 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Val 19 | - | expression tag |
| Ser 20 | - | expression tag |
| Leu 21 | - | expression tag |
| Leu 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Val 24 | - | expression tag |
| Leu 25 | - | expression tag |
| Leu 26 | - | expression tag |
| Met 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Cys 29 | - | expression tag |
| Val 30 | - | expression tag |
| Ala 31 | - | expression tag |
| Glu 32 | - | expression tag |
| Thr 33 | - | expression tag |
| Gly 34 | - | expression tag |
| Gly 271 | - | expression tag |
| Thr 272 | - | expression tag |
| Lys 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
| His 277 | - | expression tag |
| His 278 | - | expression tag |
| His 279 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128975.8 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1905.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1105.6 | |
| All* | Total formula weight | 131987.2 |
